Santanu started playing the guitar at the age of 15 and was largely self-taught during the initial years. His guitar music is unique with an effort to capture the spirit of Indian music within the Spanish instrument. A decisive point in his career as a guitarist was the meeting with the French lutist and guitarist François Martin in 2011 in Paris, with whom he studied for four years and completed the DEM (Diplôme d'Étude Musicale) and FTCL (Fellow of Trinity College London) and LRSM (Licentiate of Royal Schools of Music) in guitar performance. Santanu also took Chamber Music lessons with the French violinist Jacques Maillard and played with various instrumental ensembles.
Santanu plays a variety of musical styles on the classical guitar and often collaborates with different performers. Santanu has performed at various venues in France and India and composed several pieces for the instrument